“Empowering Women Leading the Fight Against Cancer”
Ovarian cancer remains one of the most lethal Gynecologic malignancies worldwide due to late-stage diagnosis and limited targeted therapeutic options. Folate Receptor Alpha (FRα), a glycosylphosphatidylinositol- anchored membrane protein involved in folate transport, is overexpressed in a large proportion of epithelial ovarian carcinomas, particularly high- grade serous carcinoma, while its expression in normal tissues remains…
Researchers have discovered what appears to be a critical biological driver of the most common form of ovarian cancer. The discovery, they believe, could spearhead the development of approaches for finding ovarian cancer at its earliest stages or preventing the disease from taking hold in the first place. Multiple studies have shown that high-grade serous ovarian cancer…
Summary: Scientists in Japan have discovered that a natural compound found in a type of ginger called kencur can throw cancer cells into disarray by disrupting how they generate energy. While healthy cells use oxygen to make energy efficiently, cancer cells often rely on a backup method. This ginger-derived molecule doesn t attack that method…
Our latest analysis of UK skin cancer data suggests that the way people dress when they’re in the sun could be influencing where they get melanoma – the most serious form of skin cancer. Data from 2018 to 2021 shows that 40% of melanomas in men were diagnosed on the torso (the back, chest and stomach) –…
Genetic factors contribute to some 30% of breast cancer cases in SA, necessitating investment in genomic research in African contexts. A seminal genetic study published in Nature Communication has discovered two genetic variants linked to breast cancer in black South African women, deepening knowledge about the genetic basis for this disease in African populations. The genome-wide association…
Prostate cancer is the most common cancer in males in the UK, and it accounts for 14% of all cancer deaths in males (2017 – 2019). While treatment for prostate cancer has improved over time, and 10-year survival has more than tripled in the last 50 years in the UK, prostate cancer remains one of…
PRRDetect is a major step forward in using genomics – the study of all the information in a person’s DNA – to unlock better insights into cancer. Before now, genomic sequencing (or DNA reading) tests have mostly been used to look for specific cancer-driving mutations (like changes to BRCA genes) that doctors can target with specific drugs. The…
The solution to the first problem arrived in the early 2010s, when researchers in the Netherlands developed a completely new way to study living systems: organoids. “Organoids are microscopic, three-dimensional models for studying how cells self-organise into tissues,” says Chris. They’re created from specialised cells called stem cells. When these cells divide, one of the…
Breast MRI Features May Predict Second Cancer Risk in Breast Cancer Survivors Women with a personal history of breast cancer face an elevated risk of developing a second breast cancer, particularly if they have dense breast tissue. A recent study published in Radiology, the journal of the Radiological Society of North America (RSNA), sheds light on…
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