The role of PARP inhibitors in the first line maintenance therapy in Ovarian cancer
Most patients with newly diagnosed Ovarian cancer will have advanced disease. Nearly 70% of women relapse within 3 years of first-line treatment. There is a significant need for better first-line treatment to improve outcomes for women with advanced ovarian cancer. Approximately 50% of patients with high grade serous ovarian cancer have HRD. BRCA1 and BRCA2…